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Lipoic acid (DL, α)

Overview
Catalog # bs-83089c-5-g
Product Name Lipoic acid (DL, α)
Specifications
Storage Buffer White or off-white solid
Storage Condition -20°C
Target
Product Information Endogenous antioxidant.1,2 Treatment with alpha-lipoic acid increased hepatic nuclear Nrf2 levels, induced Nrf2-mediated gene transcription, and reversed age-related decline in hepatic glutathione levels in a rat model.3 It is an essential cofactor required for catalysis by multiple mitochondrial enzymes including pyruvate dehydrogenase, α-ketoglutarate dehydrogenase and branched-chain ketoacid dehydrogenase among others.4 It has shown efficacy as a treatment in diabetic neuropathy.5
Description CAS Number: 1077-28-7

Chemical Name: (±)-1,2-Dithiolane-3-pentanoic acid

Molecular weight: 206.32

Formula: C8H14O2S2

Solubility: DMSO (30 mg/ml)

Physical Properties: Pale-yellow solid

Purity: >98% by TLC NMR (Conforms)