RepSox
Overview | |
Catalog # | bs-82912c-5-mg |
Product Name | RepSox |
Specifications | |
Storage Buffer | White solid |
Storage Condition | -20°C |
Target | |
Product Information | RepSox is a potent (IC50 ALK5 auto-P= 4 nM; IC50 TGF-b cellular assay = 23 nM) inhibitor of the TGF-β type I receptor (ALK5).1 RepSox can replace Sox2 in reprogramming adult cells into pluripotent stem cells via induction of Nanog transcription.2 It was able to convert astrocytes into neuronal cells as part of a small molecule cocktail (along with valproic acid and CHIR99021).3,4 |
Description | CAS Number: 446859-33-2 Chemical Name: 2-(3-(6-Methylpyridine-2-yl)-1H-pyrazol-4-yl)-1,5-naphthyridine; E-616452; SNJ 2511 Molecular weight: 287.32 Formula: C17H13N5 Solubility: DMSO (>25 mg/ml) Ethanol (10 mg/ml) Physical Properties: Pale yellow solid Purity: 99% by HPLC, NMR (Conforms) |