Mitapivat
Overview | |
Catalog # | bs-82875c-5-mg |
Product Name | Mitapivat |
Specifications | |
Storage Buffer | White to off-white solid |
Storage Condition | -20°C |
Target | |
Product Information | Potent (AC50 = 29 nM PKR; 37 nM PKM2; 33 nM PKL) allosteric activator of pyruvate kinase.1 In clinical use for the treatment of hemolytic anemia2 and a potential agent for the treatment for ß-thalassemia3 and sickle cell anemia4. |
Description | CAS Number: 1260075-17-9 Chemical Name: N-[4-[4-(Cyclopropylmethyl)piperazine-1-carbonyl]phenyl]quinoline-8-sulfonamide Molecular weight: 450.56 Formula: C24H26N4O3S Solubility: DMSO (>50 mg/ml) Physical Properties: Beige solid Purity: 99% by HPLC NMR (Conforms) |