Overview |
bs-8280R-PE |
DNAJC7 Polyclonal Antibody, PE Conjugated |
WB |
Human, Mouse, Rat |
Dog, Cow, Pig, Horse, Chicken, Rabbit |
Specifications |
PE |
Rabbit |
KLH conjugated synthetic peptide derived from human DNAJC7 |
221-320/494 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
7266 |
Q99615 |
Cytoplasm, Nucleus |
DnaJ homolog subfamily C member 7; Tetratricopeptide repeat protein 2; TPR repeat protein 2; TPR2; TTC2; DNJC7_HUMAN. |
The DnaJ family is one of the largest of all the chaperone families and has evolved with diverse cellular localization and functions. The presence of the J domain defines a protein as a member of the DnaJ family. DnaJ heat shock induced proteins are from the bacterium Escherichia coli and are under the control of the htpR regulatory protein. The DnaJ proteins play a critical role in the HSP 70 chaperone machine by interacting with HSP 70 to stimulate ATP hydrolysis. The proteins contain cysteine rich regions that are composed of zinc fingers that form a peptide-binding domain responsible for the chaperone function. DnaJ proteins are important mediators of proteolysis and are in-volved in the regulation of protein degradation, exocytsis and endocytosis. DnaJC7 (DnaJ homolog subfamily C member 7), also known as TPR2, TTC2 or DANJC7, is ubiquitously expressed, with highest expression in testis, liver, heart and brain. |
Application Dilution |
WB |
1:300-5000 |