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(R)-PFI-2 HCl

Overview
Catalog # bs-82771c-5-mg
Product Name (R)-PFI-2 HCl
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information Potent (IC50 = 2nM) and selective SAM-dependent inhibitor of the lysine methyltransferase SETD7.1 It alters Hippo pathway signaling in MCF7 cells by altering YAP nuclear localization in a SETD7-dependent manner.
Description CAS Number: 1627607-87-7

Chemical Name: (1R)-1-[[3-(Trifluoromethyl)phenyl]methyl]-2-oxo-2-(1-pyrrolidinyl)ethyl-1,2,3,4-tetrahydro-6-isoquinolinesulfonamide hydrochloride

Molecular weight: 535.98

Formula: C23H25F4N3O3S HCl

Solubility: DMSO (>25 mg/ml)

Physical Properties: White solid

Purity: 98% by TLC NMR (Conforms)