JNJ-63533054
Overview | |
Catalog # | bs-82716c-5-mg |
Product Name | JNJ-63533054 |
Specifications | |
Storage Buffer | White solid |
Storage Condition | -20°C |
Target | |
Product Information | Potent and selective brain-penetrant GPR139 agonist (EC50=16 nM) an orphan G-protein-coupled receptor expressed in the CNS.1 Tritium-labeled JNJ-63533054 binds to cell membranes expressing GPR139 and can be displaced by putative endogenous ligands.2 Decreases compulsive-like alcohol drinking and hyperalgesia in alcohol-dependent rodents.3 Suppresses morphine intake in a mouse self-administration model.4 |
Description | CAS Number: 1802326-66-4 Chemical Name: (S)-3-Chloro-N-(2-oxo-2-((1-phenylethyl)amino)ethyl) benzamide Molecular weight: 316.78 Formula: C17H17ClN2O2 Solubility: DMSO (35 mg/ml) Physical Properties: White solid Purity: 98% by HPLC NMr (Conforms) |