Santacruzamate A
Overview | |
Catalog # | bs-82697c-5-mg |
Product Name | Santacruzamate A |
Specifications | |
Storage Buffer | Yellow solid |
Storage Condition | -20°C |
Target | |
Product Information | A highly potent and selective inhibitor of HDAC2 isolated from the Panamanian marine cyanobacterium cf. Symploca (IC50=0.119 and 434 nM for HDAC2 and HDAC6 respectively).1 Induces apoptosis and cancer cell death only in combination with other HDAC1 inhibitors.2 Potential therapeutic agent for breast cancer.3 Attenuates A fragment (A25-35)-induced toxicity in PC12 cells by enhancing ER stress tolerance.4 Ameliorates Alzheimer’s disease-like pathology in mouse models.4 |
Description | CAS Number: 1477949-42-0 Chemical Name: N-[4-Oxo-4-[(2-phenylethyl)amino]butyl]-carbamic acid, ethyl ester Molecular weight: 278.35 Formula: C15H22N2O3 Solubility: DMSO (25 mg/ml) Ethanol (20 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms) |