Erastin
Overview | |
Catalog # | bs-82674c-5-mg |
Product Name | Erastin |
Specifications | |
Storage Buffer | Off-white solid |
Storage Condition | -20°C |
Target | |
Product Information | Ferroptosis inducer.1 Inhibits the cystine-glutamate antiporter, system Xc- leading to activation of an ER stress response.2 Inhibition of system Xc- leads to cysteine starvation, glutathione depletion and induction of ferroptosis.3 Also blocks mitochondrial voltage-dependent anion channels (specifically VDAC2 and 3).4 |
Description | CAS Number: 571203-78-6 Chemical Name: 2-[1-[4-[2-(4-Chlorophenyoxy)acetyl]-1-piperazinyl]ethyl]-3-(2-ethoxyphenyl)-4(3H)-quinazolinone Molecular weight: 547.04 Formula: C30H31ClN4O4 Solubility: DMSO (10 mg/ml) Physical Properties: White solid Purity: 98% by HPLC, NMR (Conforms) |