NSC59984
Overview | |
Catalog # | bs-82648c-5-mg |
Product Name | NSC59984 |
Specifications | |
Storage Buffer | White solid |
Storage Condition | -20°C |
Target | |
Product Information | p53 activator. Restores wild-type p53 signaling and depletes mutant p53 gain of function. Induces mutant p53 protein degradation via MDM2 and ubiquitin-proteasome pathway. Induces p73-dependent cell death in cancer cells without toxicity toward normal cells.1 Inhibition of p53-MDM2 interaction remains a viable strategy for cancer therapeutic development.2,3 |
Description | CAS Number: 803647-40-7 Chemical Name: (E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one Molecular weight: 265.27 Formula: C12H15N3O4 Solubility: DMSO (20 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC NMR (Conforms) |