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(5Z)-7-Oxozeaenol

Overview
Catalog # bs-82632c-1-mg
Product Name (5Z)-7-Oxozeaenol
Specifications
Storage Buffer White solid
Storage Condition -20°C
Target
Product Information Potent and selective inhibitor of TAK1 (mitogen activated protein kinase kinase kinase) IC50 = 8 nM.1 Selective over MEKK1 and MEKK4. Blocks IL-1-induced activation of TAK1 in cell culture.1 Blocks the production of pro-inflammatory cytokines and displays anti-inflammatory activity in various models.2-4
Description CAS Number: 253863-19-3

Chemical Name: (3S,5Z,8S,9S,11E)-3,4,9,10-Tetrahydro-8,9,16-trihydroxy-14-methoxy-3-methyl-1H-2-benzoxacyclotetradecin-1,7(8H)-dione

Molecular weight: 362.38

Formula: C19H22O7

Solubility: DMSO (9 mg/ml) Ethanol (3 mg/ml)

Physical Properties: White to off-white solid

Purity: >98% by HPLC NMR (Conforms)