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1,4-DPCA

Overview
Catalog # bs-82617c-5-mg
Product Name 1,4-DPCA
Specifications
Storage Buffer Off-white or beige solid
Storage Condition RT
Target
Product Information Potent inhibitor of prolyl 4-hydroxylase (IC50=2-4 μM)1. Inhibits collagen deposition via inhibition of collagen proline hydroxylation2,3. Subcutaneous injection of a 1,4-DPCA containing hydrogel into Swiss Webster mice that do not show a regenerative phenotype increased expression of HIF1α over 5 days. Multiple injections led to regenerative wound healing after ear hole punch injury4.
Description CAS Number: 331830-20-7

Chemical Name: 1,4-Dihydrophenonthrolin-4-one-3-carboxylic acid

Molecular weight: 240.22

Formula: C13H8N2O3

Solubility: DMSO 15 mg/ml

Physical Properties: Off-white solid

Purity: 98% by HPLC, NMR (Conforms)