SB-431542
Overview | |
Catalog # | bs-82496c-5-mg |
Product Name | SB-431542 |
Specifications | |
Storage Buffer | White solid |
Storage Condition | RT |
Target | |
Product Information | Potent and selective ALK4, ALK5 and ALK7 inhibitor (TGFβ superfamily Type I activin receptor-like kinase). (ALK5 IC50 = 94 nM)1,2. Inhibits TGFβ-induced proliferation of human osteosarcoma cells3. Ehances growth and integrity of embryonic stem cell-derived endothelial cells4. A frequently used agent employed in numerous stem cell differentiation protocols5. Cell permeable. |
Description | CAS Number: 301836-41-9 Chemical Name: 4-[4-(1,3-Benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide Molecular weight: 384.40 Formula: C22H16N4O3 Solubility: DMSO (30 mg/ml) Ethanol (3 mg/ml) Physical Properties: Yellow solid Purity: 99% by HPLC NMR (Conforms) |