Jervine
Overview | |
Catalog # | bs-82479c-5-mg |
Product Name | Jervine |
Specifications | |
Storage Buffer | Orange solid |
Storage Condition | -20°C |
Target | |
Product Information | Inhibitor of Hedgehog signaling (IC50 = 0.5-0.7 μM). Binds directly to Smoothened (Smo)1. Inhibits the response of target tissues to Sonic hedgehog signaling2. Induces COX-2 overexpression in human erythroleukemia cells3. |
Description | CAS Number: 469-59-0 Chemical Name: (3β,23β)-17,23-Epoxy-3-hydroxyveratraman-11-one Molecular weight: 425.62 Formula: C27H39NO3 Solubility: DMSO (5 mg/ml) DMF (6 mg/ml) Ethanol (20 mg/ml) Physical Properties: White solid Purity: 98% by TLC, NMR (Conforms) |