BMS-303141
Overview | |
Catalog # | bs-82230c-5-mg |
Product Name | BMS-303141 |
Specifications | |
Storage Buffer | Off-white solid |
Storage Condition | -20°C |
Target | |
Product Information | Potent and selective ATP citrate lyase (ACL) inhibitor, IC50=0.13 M. Inhibits lipid biosynthesis, IC50=8 M in HepG2 cells.1,2 Reduces weight gain, lowers plasma cholesterol, triglycerides and glucose in high-fat-fed mice.2 A novel tool compound for exploring the potential of ACL inhibition as a target for metabolic disorders such as obesity and dyslipidemia.2 Impairs proliferation or induces death in androgen-depleted castration resistant prostate cancer cells.3 Reduces cell cycle progression in iBN cells.4 |
Description | CAS Number: 943962-47-8 Chemical Name: 3,5-Dichloro-2-hydroxy-N-(4-methoxy[1,1’-biphenyl]-3-yl)-benzenesulfonamide Molecular weight: 424.30 Formula: C19H15Cl2NO4S Solubility: DMSO (25 mg/ml) Ethanol (20 mg/ml) Physical Properties: White solid Purity: 98% by TLC NMR (Conforms) |