CUR 61414
Overview | |
Catalog # | bs-82217c-5-mg |
Product Name | CUR 61414 |
Specifications | |
Storage Buffer | White solid |
Storage Condition | -20°C |
Target | |
Product Information | Novel Hedgehog signaling pathway inhibitor (IC50=100-200 nM). Selectively binds to Smo but not other GPCRs. Blocks the formation of and induces the regression of basaloid lesions in skin punches and shrinks UV-induced basaloid lesions in adult mouse skin. Cell permeable. |
Description | CAS Number: 334998-36-6 Chemical Name: N-[(3S,5S)-1-(1,3-Benzodioxol-5-ylmethyl)-5-(1-piperazinylcarbonyl)-3-pyrrolidinyl]-N-[(3-methoxyphenyl)methyl]-3,3-dimethylbutanamide Molecular weight: 550.71 Formula: C31H42N4O5 Solubility: DMSO (40 mg/ml) Ethanol (20 mg/ml) Physical Properties: Tan solid Purity: 98% by TLC, NMR (Conforms) |