Mirin
Overview | |
Catalog # | bs-82048c-5-mg |
Product Name | Mirin |
Specifications | |
Storage Buffer | Tan solid |
Storage Condition | -20°C |
Target | |
Product Information | Mirin is an inhibitor of the Mre11-Rad50-Nbs1(MRN) complex (IC50 = 12 µM for inhibition of ATM activity), part of the MRN-ATM(ataxia-telangiectasia mutated) pathway, an essential pathway for sensing and signaling from DNA double-strand breaks. Mirin abolishes the G2/M checkpoint and homology-dependent repair in mammalian cells. |
Description | CAS Number: 299953-00-7 Chemical Name: 5-(4-Hydroxybenzylidene)-2-imino-1,3-thiazolidin-4-one Molecular weight: 220.25 Formula: C10H8N2O2S Solubility: DMSO (30 mg/ml) Physical Properties: Tan solid Purity: 98% by TLC, NMR Conforms |