MK-886
Overview | |
Catalog # | bs-82026c-5-mg |
Product Name | MK-886 |
Specifications | |
Storage Buffer | White solid |
Storage Condition | RT |
Target | |
Product Information | Inhibitor of leukotriene biosynthesis(IC50 = 2.5 nM in human PMN)1 via 5-lipoxygenase-activating protein (FLAP) inhibition (IC50 = 30 nM)2. Also inhibits PPARα (80% inhibition at 10 µM).3 |
Description | CAS Number: 118414-82-7 Chemical Name: 3-[1-(4-chlorobenzyl)-3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid Molecular weight: 472.08 Formula: C27H34ClNO2S Solubility: DMSO (40 mg/ml) Physical Properties: White solid Purity: 98% by TLC [ 5% methanol in methylene chloride; Rf = 0.35] NMR conforms |