Overview |
bs-8164R-APC |
TBL1Y Polyclonal Antibody, APC Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Human, Mouse, Rat, Dog, Cow, Pig, Horse, Chicken, Rabbit |
Specifications |
APC |
Rabbit |
KLH conjugated synthetic peptide derived from human TBL1Y |
351-450/522 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
90665 |
Nucleus |
Y-linked; F-box-like/WD repeat-containing protein TBL1Y; TBL1; TBL1Y; TBL1Y_HUMAN; Transducin beta like 1, Y linked; Transducin beta-like 1; Transducin beta-like protein 1Y; Transducin-beta-like protein 1; Transducin-beta-like protein 1, Y-linked. |
FunctionF-box-like protein involved in the recruitment of the ubiquitin/19S proteasome complex to nuclear receptor-regulated transcription units. Plays an essential role in transcription activation mediated by nuclear receptors. Probably acts as integral component of corepressor complexes that mediates the recruitment of the 19S proteasome complex, leading to the subsequent proteasomal degradation of transcription repressor complexes, thereby allowing cofactor exchange. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |