Evodiamine
Overview | |
Catalog # | bs-80487C |
Product Name | Evodiamine |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:303.36 Formula:C19H17N3O Purity:>98% Solubility:Soluble in DMSO (up to 5 mg/ml). Chemical Name:8,13,13b,14-Tetrahydro-14-methylindolo[2’,3’-3-4]pyrido[2,1-b]quinazolin-5-[7H]-one |
Description | Evodiamine is a quinolone alkaloid isolated from Evodia rutaecarpa.1 Evodia Rutaecarpa is a very popular herb used in traditional chinese medicine to treat a variety of ailments. It has been shown to elicit a variety of biological effects including induction of apoptosis, inhibiting cancer cell proliferation, promoting cell cycle arrest in G2/M, inhibiting invasion and metastasis of cancer cells, inhibiting angiogenesis, induction of oxidative stress and subsequent apoptosis and inhibition of NF-κB.2 It also functions as an agonist of TRPV1 (EC50 = 1.03 µM)3 and acts as an anti-inflammatory agent4. |