Mithramycin A
Overview | |
Catalog # | bs-80399C |
Product Name | Mithramycin A |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:1085.15 Formula:C52H76O24 Purity:>98% Solubility:Soluble in DMSO (up to 20 mg/ml) or in Ethanol (up to 10 mg/ml). Chemical Name: |
Description | Inhibits DNA methyl transferase1. A selective Sp1 inhibitor, it binds to GC rich DNA sequences, displacing Sp1 transcription factor binding to oncogene promoters, inhibitings their expression2. Mithramycin A (at 10-200 nM) sensitizes tumor cells to TRAIL-induced apoptosis3. |