NSC632839
Overview | |
Catalog # | bs-80225C |
Product Name | NSC632839 |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:339.86 Formula:C21H21NO · HCl Purity:>98% Solubility:Soluble in DMSO (up to 8 mg/ml). Chemical Name:3,5-Bis[(4-methylphenyl)methylene]-4-piperidone hydrochloride |
Description | A pan-specific ubiquitin isopeptidase inhibitor. (IC50= 45, 37 and 9.8 μM for USP2, USP7 and SENP2 respectively) Does not effect proteasome proteolytic activity. Induces apoptosis via a Bcl-2-dependent but apoptosome-independent mitochondrial pathway1,2. Cell permeable. |