NSC66811
Overview | |
Catalog # | bs-80192C |
Product Name | NSC66811 |
Specifications | |
Storage Buffer | powder |
Storage Condition | RT |
Target | |
Product Information | Molecular Weight:340.43 Formula:C23H20N2O Purity:>98% Solubility:Soluble in DMSO (up to 25 mg/ml). Chemical Name:2-Methyl-7-[Phenyl(phenylamino)methyl]-8-quinolinol |
Description | A novel inhibitor of the MDM2-p53 interaction. Mimics three p53 residues involved in binding to MDM2. Binds to MDM2 with a Ki of 120 nM. Activates p53 in cancer cells. Cell permeable. |