IWP-2
Overview | |
Catalog # | bs-80178C |
Product Name | IWP-2 |
Specifications | |
Storage Buffer | powder |
Storage Condition | -20°C |
Target | |
Product Information | Molecular Weight:466.61 Formula:C22H18N4O2S3 Purity:>98% Solubility:Soluble in DMSO (up to 5 mg/ml, with warming). Chemical Name:N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide |
Description | IWP-2 is an inhibitor of Wnt secretion and processing. It blocks Wnt-dependent signaling (IC50=27nM) by inhibition of the O-acyltransferase Porcn1. Induces cardiomyocyte differentiation from human pluripotent stem cells2. An important tool to probe the involvement of the Wnt pathway in physiological processes3,4. Cell permeable. |