PLX4720
Overview | |
Catalog # | bs-75487c-5mg |
Product Name | PLX4720 |
Specifications | |
Storage Buffer | Solid |
Storage Condition | Stable for 2 years after receipt when stored at -20°C. |
Target | |
Product Information | CAS Number: 918505-84-7 Molecular formula: C17H14ClF2N3O3S Molecular weight: 413.8 Purity: >99% (HPLC) Appearance: Off-white solid. Solubility: Soluble in DMSO or ethanol. InChiKey: YZDJQTHVDDOVHR-UHFFFAOYSA-N SMILES: CCCS(=O)(=O)NC1=CC=C(F)C(C(=O)C2=CNC3=NC=C(Cl)C=C23)=C1F |
Description | Potent and selective cell permeable B-Raf (V600E) and c-Raf-1 (Y340D/Y341D) inhibitor. Antitumor compound. ERK phosphorylation is potently inhibited exclusive in B-Raf(V600E)-bearing tumor cell lines. |