(R,R)-Hymeglusin
| Overview | |
| Catalog # | bs-75085C |
| Product Name | (R,R)-Hymeglusin |
| Specifications | |
| Storage Buffer | Solid |
| Storage Condition | Stable for 3 years after receipt when stored at -20°C. |
| Target | |
| Product Information | CAS Number: 29066-42-0 Molecular formula: C18H28O5 Molecular weight: 324.4 Purity: >95% (HPLC) Appearance: White to off-white solid. Solubility: Soluble in methanol, ethanol, DMSO, chloroform or ethyl acetate. Insoluble in water or hexane. InChiKey: ODCZJZWSXPVLAW-KXCGKLMDSA-N SMILES: C[C@H](CCCC[C@H]1OC(=O)[C@@H]1CO)C\C(C)=C\C(\C)=C\C(O)=O |
| Description | beta-Lactone antibiotic [1]. Antibacterial and antifungal [1, 4]. Specific and irreversible inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) synthase in vitro and in vivo by covalently modifying the active Cys129 residue of the enzyme [2-4, 6-8]. Mevalonate biosynthesis inhibitor [5]. |
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