Epetraborole hydrochloride
Overview | |
Catalog # | bs-6629c-10mg-solid |
Product Name | Epetraborole hydrochloride |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 273.52 Formula: C11 H17 B Cl N O4 CAS Number: 1234563-16-6 InChi Key: DADYQGIQOBJGIW-HNCPQSOCSA-N InChi: InChI=1S/C11H16BNO4.ClH/c13-7-10-8-3-1-4-9(16-6-2-5-14)11(8)12(15)17-10;/h1,3-4,10,14-15H,2,5-7,13H2;1H/t10-;/m1./s1 Smiles: Cl.NC[C@H]1OB(O)C2=C1C=CC=C2OCCCO Purity: 98.0 Solubility: Soluble in DMSO, not in water Appearance: Solid Power. Shelf Life: 1.0 years |
Description | Epetraborole, also known as GSK2251052 and AN3365, is a potent and selective leucyl-tRNA synthetase inhibitor. Epetraborole was in development for the treatment of infections caused by multidrug-resistant Gram-negative pathogens. GSK2251052 is a novel boron-containing antibiotic that inhibits bacterial leucyl tRNA synthetase. All Clostridium perfringens strains had GSK2251052 MICs of >32 μg/ml. |