CW069
Overview | |
Catalog # | bs-6570c-10mg-solid |
Product Name | CW069 |
Specifications | |
Storage Buffer | Powder |
Storage Condition | Store in dry, dark place at -20C for 1 year. |
Target | |
Product Information | Molecular Weight: 500.33 Formula: C23 H21 I N2 O3 CAS Number: 1594094-64-0 InChi Key: IRDIXDXDSUBHIU-NRFANRHFSA-N InChi: InChI=1S/C23H21IN2O3/c24-18-11-12-20(19(14-18)23(28)29)26-22(27)21(13-16-7-3-1-4-8-16)25-15-17-9-5-2-6-10-17/h1-12,14,21,25H,13,15H2,(H,26,27)(H,28,29)/t21-/m0/s1 Smiles: OC(=O)C1C=C(I)C=CC=1NC(=O)[C@H](CC1C=CC=CC=1)NCC1C=CC=CC=1 Purity: 98.0 Solubility: Soluble in DMSO Appearance: Solid Power Shelf Life: 1.0 years |
Description | CW069 is an allosteric inhibitor of HSET. CW069 showed marked activity against HSET in vitro. The inhibitor induced multipolar mitoses only in cells containing supernumerary centrosomes. CW069 therefore constitutes a valuable tool for probing HSET function and, by reducing the growth of cells containing supernumerary centrosomes, paves the way for new cancer therapeutics. |