Overview |
bs-5751R-Cy3 |
MATK Polyclonal Antibody, Cy3 Conjugated |
WB, IF(IHC-P), IF(IHC-F), IF(ICC) |
Human, Mouse, Rat, Dog, Cow, Pig, Horse |
Specifications |
Cy3 |
Rabbit |
KLH conjugated synthetic peptide derived from human MATK |
411-507/507 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
4145 |
Cytoplasm, Cell membrane |
CHK; Csk homologous kinase; Csk type protein tyrosine kinase; CTK; Hematopoietic consensus tyrosine lacking kinase; HHYLTK; Hydroxyaryl protein kinase; HYL; HYL tyrosine kinase; HYLTK; Leukocyte carboxyl terminal src kinase related; Lsk; Megakaryocyte associated tyrosine kinase; Megakaryocyte associated tyrosine protein kinase; Protein kinase HYL; Tyrosine kinase MATK; Tyrosine protein kinase CTK; Tyrosylprotein kinase; MATK_HUMAN. |
The protein encoded by this gene has amino acid sequence similarity to Csk tyrosine kinase and has the structural features of the CSK subfamily: SRC homology SH2 and SH3 domains, a catalytic domain, a unique N terminus, lack of myristylation signals, lack of a negative regulatory phosphorylation site, and lack of an autophosphorylation site. MATK is thought to play a significant role in the signal transduction of hematopoietic cells. It is able to phosphorylate and inactivate Src family kinases, and may play an inhibitory role in the control of T-cell proliferation. This protein might be involved in signaling in some cases of breast cancer. |
Application Dilution |
WB |
1:300-5000 |
IF(IHC-P) |
1:50-200 |
IF(IHC-F) |
1:50-200 |
IF(ICC) |
1:50-200 |