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MeCP2 Polyclonal Antibody

Applications

  • WB
  • ELISA
  • dot-blot

Reactivity

  • Human
Overview
Catalog # bs-53112R
Product Name MeCP2 Polyclonal Antibody
Applications WB, ELISA, dot-blot
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Polyclonal antibody raised in rabbit against MeCP2 (Methyl-CpG-binding domain protein 2), using a KLH-conjugated synthetic peptide containing a sequence from the C-terminal part of the protein
Clonality Polyclonal
Isotype Not Determined
Concentration 1.2ug/ul
Purification Affinity purified polyclonal antibody in PBS containing 0.05% azide and 0.05% ProClin 300.
Storage Buffer PBS with 0.05% sodium azide and 0.05% Proclin300.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 4204
Swiss Prot P51608
Synonyms Methyl-CpG-binding protein 2, MECP2, MeCp-2 protein
Background Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the corepressor SIN3A. Binds both 5-methylcytosine (5mC) and 5-hydroxymethylcytosine (5hmC)-containing DNA, with a preference for 5-methylcytosine (5mC).
Application Dilution
WB 1:300-5000
ELISA 1:500-1000
dot-blot