| Overview |
| bs-51025R |
| 5-hmC Monoclonal Antibody(mouse) |
| WB |
| Human |
| Specifications |
| Unconjugated |
| Mouse |
| Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively |
| Monoclonal |
| . |
| IgG1 |
| 0.6ug/ul |
| Protein G purified monoclonal antibody in PBS containing 0.05% azide. |
| PBS with 0.05% sodium azide. |
| Store at -20°C for 12 months. |
| Target |
| 4999 |
| Q13416 |
| ORC2L, Origin recognition complex subunit 2, ORC2 |
| Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3. |
| Application Dilution |
| WB |
1:300-5000 |
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