Recombinant human NCR1 protein, N-His
Applications
Reactivity
Overview | |
Catalog # | bs-41214P |
Product Name | Recombinant human NCR1 protein, N-His |
Applications | ELISA |
Reactivity | Others |
Specifications | |
Conjugation | Unconjugated |
Storage Buffer | 0.01M TBS(pH7.4) |
Storage Condition | The product should be stored at -70°C or -20°C. |
Target | |
Gene ID | 9437 |
Swiss Prot | O76036 |
Background | The natural cytotoxicity receptors (NCRs) are a recently characterized family of Ig-like activation receptors that appear to be major triggering receptors in tumor cell recognition. NCR1 is a glycoprotein that has two extracellular Ig-like domains followed by a ~40 amino acid residue stalk region, a type I transmembrane domain, and a short cytoplasmic tail. NCR1 has been shown to represent a novel NK cell-specific molecule involved in human NK cell activation. NCR1 has been implicated in NK cell-mediated lysis of several autologous tumor cells and pathogen-infected cell lines. |