Overview |
bs-3278R-HRP |
MKP1 (Ser359) Polyclonal Antibody, HRP Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human, Rat, Dog, Cow, Pig, Chicken, Rabbit |
Specifications |
HRP |
Rabbit |
KLH conjugated synthetic phosphopeptide derived from human MKP1 around the phosphorylation site of Ser359 |
Ser359 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
1843 |
Nucleus |
Mitogen activated protein kinase phosphatase 1; CL 100; CL100; Dual Specicity Phosphatase 1; Dual specicity protein phosphatase 1; Dual specicity protein phosphatase hVH1; DUSP 1; EC 3.1.3.16; EC 3.1.3.48; HVH 1; HVH1; MAP kinase phosphatase 1; MKP 1; MKP1; MKP-1; Protein tyrosine phosphatase CL100; PTPN 10; PTPN10; Serine/threonine specic protein phosphatase; VH 1; VH1; 3ch134; Mkp1; Ptpn16. |
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |