Overview |
bs-19654R-Cy7 |
Phospho-OLIG2 (Ser10+Ser13+Ser14) Polyclonal Antibody, Cy7 Conjugated |
WB, FCM |
Expressed in the brain, in oligodendrocytes. Strongly expressed in oligodendrogliomas, while expression is weak to moderate in astrocytomas. Expression in glioblastomas highly variable. |
Human |
Mouse, Rat, Cow, Chicken |
Specifications |
Cy7 |
Rabbit |
KLH conjugated synthesized phosphopeptide derived from human OLIG2 around the phosphorylation site of Ser10+Ser13+Ser14: VS(pS)RP(pS)(pS)PE |
Ser10+Ser13+Ser14 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target |
10215 |
Q13516 |
Cytoplasm, Nucleus |
Olig2 (phospho S10 + S13 + S14); p-Olig2 (phospho S10 + S13 + S14); Basic domain helix loop helix protein class B 1; Basic helix loop helix protein class B 1; BHLHB; bHLHB1; bHLHe19; Class B basic helix loop helix protein 1; Class B basic helix-loop-helix protein 1; class E basic helix loop helix protein 19; Class E basic helix-loop-helix protein 19; Human protein kinase C binding protein RACK17; Olig2; OLIG2_HUMAN; Oligo2 ; Oligodendrocyte lineage transcription factor 2; Oligodendrocyte specific bHLH transcription factor 2; Oligodendrocyte transcription factor 2; OTTHUMP00000067569; OTTHUMP00000067570; PRKCBP2; -binding protein RACK17; RACK17. |
This gene encodes a basic helix-loop-helix transcription factor which is expressed in oligodendroglial tumors of the brain. The protein is an essential regulator of ventral neuroectodermal progenitor cell fate. The gene is involved in a chromosomal translocation t(14;21)( q11.2;q22) associated with T-cell acute lymphoblastic leukemia. Its chromosomal location is within a region of chromosome 21 which has been suggested to play a role in learning deficits associated with Down syndrome. [provided by RefSeq, Jul 2008] |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |