Overview |
bs-0032R-Biotin |
Bcl-2 Polyclonal Antibody, Biotin Conjugated |
WB, ELISA, IHC-P, IHC-F |
Human, Mouse, Rat, Bovine, Chicken, Rabbit, Bacteria |
Dog, Cow, Pig, Horse |
Specifications |
Biotin |
Rabbit |
KLH conjugated synthetic peptide derived from rat Bcl-2 |
101-160/236 |
Polyclonal |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
24224 |
P49950 |
Cytoplasm, Nucleus, Cell membrane |
Bcl-2; Apoptosis regulator Bcl-2; Bcl2 |
Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1). |
Application Dilution |
WB |
1:300-5000 |
ELISA |
1:500-1000 |
IHC-P |
1:200-400 |
IHC-F |
1:100-500 |