Overview |
bsm-54761R |
CTNNA3 Monoclonal Antibody |
WB, IHC-P |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
Recombinant fragment within C-terminal Human CTNNA3. |
Monoclonal |
3H55 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
29119 |
Q9UI47 |
Cytoskeleton |
4930429L08Rik antibody, 4933408A16 antibody, Alpha catenin like protein antibody, Alpha T catenin antibody, Alpha T-catenin antibody, Cadherin associated protein antibody, Cadherin-associated protein antibody, Catenin alpha 3 antibody, Catenin alpha-3 antibody, Catna3 antibody, CTNA3_HUMAN antibody, CTNNA3 antibody, MGC26194 antibody, MGC75041 antibody, OTTHUMP00000019684 antibody, OTTMUSP00000028119 antibody, OTTMUSP00000028120 antibody, RP11-433J16.1 antibody, VR22 antibody |
The catenins are ubiquitously expressed, cytoplasmic proteins that associate with E-cadherin at cellular junctions. Catenin/cadherin complexes play an important role in mediating cellular adhesion. alpha T-catenin, also referred to as VR22, is a 895-amino acid protein that is most abundantally expressed in cardiomyocytes and in the peritubular myoid cells of the testis. alpha T-catenin binds to alpha E-catenin as well as to beta-catenin, and it functions to inhibit Wnt signaling. CTNNA3, the gene that encodes for alpha-T-catenin, is located on chromosome 10, and mutations in this gene show a strong correlation to late-onset Alzheimer's disease (LOAD) as well as to dilated cardiomyopathy. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |