Overview |
bsm-54720R |
ARF5 Monoclonal Antibody |
WB, IHC-P |
Human, Mouse |
Specifications |
Unconjugated |
Rabbit |
Synthetic Peptide within C terminal Human ARF5. |
Monoclonal |
8H3 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
381 |
P84085 |
Golgi apparatus, Perinuclear region, Membrane, Trans-Golgi network membrane |
ADP ribosylation factor 5 antibody, ADP-ribosylation factor 5 antibody, ARF 5 antibody, Arf5 antibody, ARF5_HUMAN antibody |
The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins. ARFs influence vesicle trafficking and signal transduction in eukaryotic cells. ARF-dependent regulatory mechanisms include the coordination of spectrin interactions with golgi membranes and the association of actin to the golgi via rho family-dependent G-protein localization (Rac, CDC42) and WASP/Arp2/3 complexes. Additionally, ARFs play a central role in maintenance of organelle integrity, assembly of coat proteins, and activation of phospho-lipase D. The ARF proteins are categorized as class I (ARF1, ARF2, and ARF3), class II (ARF4 and ARF5) and class III (ARF6); members of each class share a common gene organization. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |