MAD3 Monoclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bsm-54664R |
Product Name | MAD3 Monoclonal Antibody |
Applications | WB, FCM |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | Synthetic Peptide within N-terminal human MAD3. |
Clonality | Monoclonal |
Clone # | 11D8 |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Storage Condition | Store at -20°C for 12 months. |
Target | |
Gene ID | 83463 |
Swiss Prot | Q9BW11 |
Subcellular location | Nucleus |
Synonyms | bHLHc13 antibody, Class C basic helix-loop-helix protein 13 antibody, FLJ35523 antibody, Likely ortholog of mouse Max dimerization protein 3 antibody, MAD3_HUMAN antibody, MAX dimerization protein 3 antibody, Max dimerizer 3 antibody, Max-associated protein 3 antibody, Max-interacting transcriptional repressor MAD3 antibody, MGC2383 antibody, mxd3 antibody, Myx antibody, OTTHUMP00000223596 antibody, OTTHUMP00000223598 antibody |
Background | This gene encodes a member of the Myc superfamily of basic helix-loop-helix leucine zipper transcriptional regulators. The encoded protein forms a heterodimer with the cofactor MAX which binds specific E-box DNA motifs in the promoters of target genes and regulates their transcription. Disruption of the MAX-MXD3 complex is associated with uncontrolled cell proliferation and tumorigenesis. Transcript variants of this gene encoding different isoforms have been described.[provided by RefSeq, Dec 2008] |
Application Dilution | |
WB | 1:300-5000 |
FCM | 1:20-100 |