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BANF1 Recombinant Antibody

Applications

  • FCM
  • IHC-P
  • IF(IHC-P)
  • IF(ICC)

Reactivity

  • Human
  • Mouse
  • Rat
Overview
Catalog # bsm-54435r-100ul
Product Name BANF1 Recombinant Antibody
Applications FCM, IHC-P, IF(IHC-P), IF(ICC)
Reactivity Human, Mouse, Rat
Specifications
Conjugation Unconjugated
Host Rabbit
Source Full length recombinant protein of human BANF1.
Clonality Recombinant
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 8815
Swiss Prot O75531
Subcellular location Cytoplasm, Nucleus
Synonyms Barrier-to-autointegration factor; Breakpoint cluster region protein 1; Barrier-to-autointegration factor N-terminally processed; BANF1; BAF; BCRG1; NGPS; BCRP1;
Background Barrier-to-autointegration factor (BANF1) binds non-specifically to double stranded DNA, possibly to play a role in tissue- or cell type-specific gene expression by interacting with different homeodomain transcription factors. BANF1 compresses chromatin structure and interacts with the LEM domain of nuclear proteins to play a crucial role in membrane recruitment and chromatin decondensation during nuclear assembly. Additionally, retroviruses like HIV-1 incorporate BANF1 from host cells into preintegration complexes (PICs) to prevent autointegration of retroviral DNA and thereby promote integration of retroviral DNA into the host chromosome.
Application Dilution
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200