Overview |
bsm-54159R |
NDUFS3 (9B7) Monoclonal Antibody |
WB, IHC-P, IF(IHC-P), IF(ICC) |
Human |
Specifications |
Unconjugated |
Rabbit |
Recombinant protein within human NDUFS3 aa 100 to the C-terminus |
Monoclonal |
9B7 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Target |
4722 |
O75489 |
Mitochondrion |
NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 mitochondrial; Complex I-30kD; NADH-ubiquinone oxidoreductase 30 kDa subunit; CI-30kD; NDUFS3; MC1DN8; NADH:ubiquinone oxidoreductase core subunit S3. |
This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency. NDUFS3 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |
IF(IHC-P) |
1:50-200 |
IF(ICC) |
1:50-200 |