Overview |
bsm-54061R |
DOPA Decarboxylase (2C12) Monoclonal Antibody |
WB, IHC-P |
Human, Mouse, Rat |
Specifications |
Unconjugated |
Rabbit |
N terminal human DOPA Decarboxylase |
Monoclonal |
2C12 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at 4C for up to 2 weeks. For long term storage, store at -20C in small aliquots to prevent freeze-thaw cycles. |
Target |
1644 |
P20711 |
Aromatic-L-amino-acid decarboxylase, DOPA decarboxylase, AADC, DDC |
The encoded protein catalyzes the decarboxylation of L-3,4-dihydroxyphenylalanine (DOPA) to dopamine, L-5-hydroxytryptophan to serotonin and L-tryptophan to tryptamine. Defects in this gene are the cause of aromatic L-amino-acid decarboxylase deficiency (AADCD). AADCD deficiency is an inborn error in neurotransmitter metabolism that leads to combined serotonin and catecholamine deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |