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ORC2 (5C3) Monoclonal Antibody

Applications

  • WB
  • IF(ICC)

Reactivity

  • Human
Overview
Catalog # bsm-53025M
Product Name ORC2 (5C3) Monoclonal Antibody
Applications WB, IF(ICC)
Reactivity Human
Specifications
Conjugation Unconjugated
Host Mouse
Source Monoclonal antibody raised in mouse against human ORC2, using two recombinant proteins containing the N-terminal and C-terminal part of the protein, respectively
Clonality Monoclonal
Clone # 5C3
Isotype IgG1
Concentration 0.6ug/ul
Purification Protein G purified monoclonal antibody in PBS containing 0.05% azide.
Storage Buffer PBS with 0.05% sodium azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 4999
Swiss Prot Q13416
Synonyms ORC2L, Origin recognition complex subunit 2, ORC2
Background Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent. The specific DNA sequences that define origins of replication have not been identified yet. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. Binds histone H3 and H4 trimethylation marks H3K9me3, H3K20me3 and H4K27me3. Stabilizes LRWD1, by protecting it from ubiquitin-mediated proteasomal degradation. Also stabilizes ORC3.
Application Dilution
WB 1:300-5000
IF(ICC) 1:50-200