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alpha 1 Antitrypsin (9C7) Monoclonal Antibody

Applications

  • WB
  • IHC-P
  • IF(ICC)
  • IHC

Reactivity

  • Human
Overview
Catalog # bsm-52866R
Product Name alpha 1 Antitrypsin (9C7) Monoclonal Antibody
Applications WB, IHC-P, IF(ICC), IHC
Reactivity Human
Specifications
Conjugation Unconjugated
Host Rabbit
Source Full length protein
Clonality Monoclonal
Clone # 9C7
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein A.
Storage Buffer Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide.
Storage Condition Store at -20°C for 12 months.
Target
Gene ID 5265
Swiss Prot P01009
Synonyms Alpha-1 protease inhibitor, Alpha-1-antiproteinase, Serpin A1, SERPINA1
Background Inhibitor of serine proteases. Its primary target is elastase, but it also has a moderate affinity for plasmin and thrombin. Irreversibly inhibits trypsin, chymotrypsin and plasminogen activator. The aberrant form inhibits insulin-induced NO synthesis in platelets, decreases coagulation time and has proteolytic activity against insulin and plasmin. Short peptide from AAT: reversible chymotrypsin inhibitor. It also inhibits elastase, but not trypsin. Its major physiological function is the protection of the lower respiratory tract against proteolytic destruction by human leukocyte elastase (HLE).
Application Dilution
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC