Overview |
bsm-52315R |
SIRT1 (3C7) Monoclonal Antibody |
WB, IF(ICC), IHC |
Human, Mouse |
Specifications |
Unconjugated |
Rabbit |
Human SIRT1 between 700-800 amino acids |
Monoclonal |
3C7 |
IgG |
1ug/ul |
Purified by Protein A. |
Aqueous buffered solution containing 1xTBS (pH7.4), 1%BSA, 40%Glycerol and 0.05% Sodium Azide. |
Store at -20°C for 12 months. |
Target |
23411 |
Q96EB6 |
NAD-dependent protein deacetylase sirtuin-1, Regulatory protein SIR2 homolog 1, SIR2-like protein 1, hSIRT1, hSIR2, SIRT1 |
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2008] |
Application Dilution |
WB |
1:300-5000 |
IF(ICC) |
1:50-200 |
IHC |
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