Overview |
bsm-51271M |
SRC (17AT28) Monoclonal Antibody |
WB |
Human, Mouse |
Specifications |
Unconjugated |
Mouse |
This Src antibody is generated from mouse immunized with a recombinant protein of full length human SRC. |
Monoclonal |
17AT28 |
IgG1 |
0.5ug/ul |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
6714 |
P12931 |
ASV; SRC1; THC6; c-SRC; p60-Src; Proto-oncogene tyrosine-protein kinase Src; Proto-oncogene c-Src; pp60c-src; SRC |
This gene is highly similar to the v-src gene of Rous sarcoma virus. This proto-oncogene may play a role in the regulation of embryonic development and cell growth. The protein encoded by this gene is a tyrosine-protein kinase whose activity can be inhibited by phosphorylation by c-SRC kinase. Mutations in this gene could be involved in the malignant progression of colon cancer. Two transcript variants encoding the same protein have been found for this gene. |
Application Dilution |
WB |
1:300-5000 |