Overview |
bsm-51040M |
PRKAA1 (7C6) Monoclonal Antibody |
WB, IHC-P |
Human |
Specifications |
Unconjugated |
Mouse |
This PRKAA1 Monoclonal antibody was raised using purified His-tagged recombinant human PRKAA1. |
Monoclonal |
7C6 |
IgG1 |
0.5ug/ul |
Mouse monoclonal antibody supplied in crude ascites with 0.09% (W/V) sodium azide. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
5562 |
Q13131 |
AMPK; AMPKa1; 5'-AMP-activated protein kinase catalytic subunit alpha-1; AMPK subunit alpha-1; Acetyl-CoA carboxylase kinase; ACACA kinase; Hydroxymethylglutaryl-CoA reductase kinase; HMGCR kinase; Tau-protein kinase PRKAA1; PRKAA1; AMPK1 |
Responsible for the regulation of fatty acid synthesis by phosphorylation of acetyl-CoA carboxylase. It also regulates cholesterol synthesis via phosphorylation and inactivation of hormone-sensitive lipase and hydroxymethylglutaryl-CoA reductase. Appears to act as a metabolic stress-sensing protein kinase switching off biosynthetic pathways when cellular ATP levels are depleted and when 5'-AMP rises in response to fuel limitation and/or hypoxia. This is a catalytic subunit. |
Application Dilution |
WB |
1:300-5000 |
IHC-P |
1:200-400 |