Overview |
bsm-51027M |
ITA6 (9C5) Monoclonal Antibody |
WB, FCM, IHC-P, IF |
Human |
Specifications |
Unconjugated |
Mouse |
ITA6 recombinant protein is used to produce this monoclonal antibody. |
Monoclonal |
9C5 |
IgG1 |
0.5ug/ul |
Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Store at -20°C for 12 months. |
Target |
3655 |
P23229 |
CD49f; VLA-6; ITGA6B; Integrin alpha-6; CD49 antigen-like family member F; ITGA6 |
Integrin alpha-6/beta-1 is a receptor for laminin on platelets. Integrin alpha-6/beta-4 is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to NRG1 (via EGF domain) and this binding is essential for NRG1-ERBB signaling (PubMed:20682778). ITGA6:ITGB4 binds to IGF1 and this binding is essential for IGF1 signaling (PubMed:22351760). |
Application Dilution |
WB |
1:300-5000 |
FCM |
1:20-100 |
IHC-P |
1:200-400 |
IF |
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