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Ki-67 Monoclonal Antibody, AbBy Fluor® 488 Conjugated

Applications

  • FCM

Reactivity

  • Human
  • Rat

Predicted Reactivity

  • Mouse
Overview
Catalog # bsm-33070M-BF488
Product Name Ki-67 Monoclonal Antibody, AbBy Fluor® 488 Conjugated
Applications FCM
Reactivity Human, Rat
Predicted Reactivity Mouse
Specifications
Conjugation AbBy Fluor® 488
Host Mouse
Source KLH conjugated synthetic peptide derived from human Ki-67
Clonality Monoclonal
Clone # 6B9
Isotype IgG
Concentration 1ug/ul
Purification Purified by Protein G.
Storage Buffer Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Storage Condition Store at -20¡C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
Target
Gene ID 4288
Swiss Prot P46013
Synonyms Antigen identified by monoclonal antibody Ki 67; Antigen KI67; KIA; Ki-67; Ki67; MKI67; Proliferation related Ki 67 antigen; Antigen KI-67; KI67_HUMAN.
Background Ki67 antigen is the prototypic cell cycle related nuclear protein, expressed by proliferating cells in all phases of the active cell cycle (G1, S, G2 and M phase). It is absent in resting (G0) cells. Ki67 antibodies are useful in establishing the cell growing fraction in neoplasms (immunohistochemically quantified by determining the number of Ki67 positive cells among the total number of resting cells = Ki67 index). In neoplastic tissues the prognostic value is comparable to the tritiated thymidine labelling index. The correlation between low Ki67 index and histologically low grade tumours is strong. Ki67 is routinely used as a neuronal marker of cell cycling and proliferation.
Application Dilution
FCM 1:20-100