FBXW5 Polyclonal Antibody
Applications
Reactivity
Overview | |
Catalog # | bs-9083R |
Product Name | FBXW5 Polyclonal Antibody |
Applications | WB, IHC-P, IF(IHC-P) |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | Unconjugated |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human FBXW5 |
Immunogen Range | 201-300/566 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | 0.01M TBS(pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
Storage Condition | Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles. |
Target | |
Gene ID | 54461 |
Synonyms | F box and WD 40 domain containing protein 5; F box and WD repeat domain containing 5; FBW5; FBXW5_HUMAN. |
Background | FBXW5 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW5 contains WD-40 domains, in addition to an F-box motif, so it belongs to the Fbw class. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene, however, they were found to be nonsense-mediated mRNA decay (NMD) candidates, hence not represented. |
Application Dilution | |
WB | 1:300-5000 |
IHC-P | 1:200-400 |
IF(IHC-P) | 1:50-200 |