ODZ3 Polyclonal Antibody, AbBy Fluor® 555 Conjugated
Applications
Reactivity
Overview | |
Catalog # | bs-9061R-BF555 |
Product Name | ODZ3 Polyclonal Antibody, AbBy Fluor® 555 Conjugated |
Applications | IF(IHC-P) |
Reactivity | Human, Mouse, Rat |
Specifications | |
Conjugation | AbBy Fluor® 555 |
Host | Rabbit |
Source | KLH conjugated synthetic peptide derived from human ODZ3/Teneurin 3 |
Immunogen Range | 1721-1850/2699 |
Clonality | Polyclonal |
Isotype | IgG |
Concentration | 1ug/ul |
Purification | Purified by Protein A. |
Storage Buffer | Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
Storage Condition | Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles. |
Target | |
Subcellular location | Extracellular |
Synonyms | ODZ3 like protein; Protein Odd Oz ten m homolog 3; Ten 3; Ten M3; Tenascin M3; Teneurin 3; Teneurin3; TNM3; FLJ10474; FLJ10886; KIAA1455; odd Oz Ten m homolog 3; odz odd Oz ten m homolog 3 Drosophila; odz odd Oz ten m homolog 3; TEN3_HUMAN. |
Background | Teneurin-3, also known as Ten-3, TNM3 or ODZ3, is a 2,699 amino acid single-pass type II membrane protein that contains 25 YD repeats, 8 EGF-like domains, 5 NHL repeats and one teneurin N-terminal domain. Localized to the membrane and expressed in brain, testis and ovary, Teneurin-3 exists as a disulfide-liked homodimer that is thought to function as a cellular signal transducer. Additionally, Teneurin-3 may participate in eye-specific patterning in the visual pathway and is required for aligned binocular vision. The gene encoding Teneurin-3 maps to chromosome 4. Representing approximately 6% of the human genome, chromosome 4 contains nearly 900 genes, one of which is the Huntingtin gene, which is found to encode an expanded glutamine tract in cases of Huntington's disease. FGFR-3 is also encoded on chromosome 4 and has been associated with thanatophoric dwarfism, achondroplasia, Muenke syndrome and bladder cancer. Chromosome 4 is also tied to Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease. |
Application Dilution | |
IF(IHC-P) | 1:50-200 |