Filgotinib
| Overview | |
| Catalog # | bs-83097c-5-mg |
| Product Name | Filgotinib |
| Specifications | |
| Storage Buffer | Yellow solid |
| Storage Condition | -20°C |
| Target | |
| Product Information | Potent and selective JAK1 inhibitor (IC50s=10, 28, 810 and 116 nM for JAK1, JAK2, JAK3 and TYK2 respectively.2 Displays potent anti-inflammatory activity in various models.1,2 Effective as a monotherapy in patients with active rheumatoid arthritis.3 Reverses oncostatin M-mediated inhibition of rat stem Leydig cell differentiation.4 |
| Description | CAS Number: 1206161-97-8 Chemical Name: N-[5-[4-[(1,1-dioxido-4-thiomorpholinyl)methyl]phenyl][1,2,4]triazolo[1,5-ɑ]pyridin-2-yl]-cyclopropanecarboxamide Molecular weight: 425.50 Formula: C21H23N5O3S Solubility: DMSO (15 mg/ml) Physical Properties: Off-white solid Purity: 98% by TLC, NMR (Conforms) |
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